DSG1 Polyclonal Antibody | G-AB-12400

DSG1 Polyclonal Antibody | G-AB-12400 | Gentaur Antibodies

Overview: This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: DSG1, CDHF4, DG1, DSG, EPKHE, EPKHIA, PPKS1, SPPK1

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 1828

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human DSG1 (NP_001933.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q02413

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:100 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

DSG1 Polyclonal Antibody DataSheet