EIF2AK3 Polyclonal Antibody | G-AB-09760

EIF2AK3 Polyclonal Antibody | G-AB-09760 | Gentaur Antibodies

Overview: The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER) , where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism

Synonyms: EIF2AK3, PEK, PERK, WRS

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 9451

Accession #:

Clonality:

Immunogen: Recombinant protein of human EIF2AK3

Clone #:

Conjugation: Unconjugated

Swissprot: Q9NZJ5

Santa Cruz:

Calculated MW: 125 kDa

Observed MW: 160 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

EIF2AK3 Polyclonal Antibody DataSheet