EIF2AK3 Polyclonal Antibody | G-AB-09760
Gentaur Antibodies
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Gentaur Antibodies
EIF2AK3 Polyclonal Antibody | G-AB-09760
- SKU:
- G-AB-09760
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
EIF2AK3 Polyclonal Antibody | G-AB-09760 | Gentaur Antibodies
Overview: The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER) , where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism
Synonyms: EIF2AK3, PEK, PERK, WRS
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 9451
Accession #:
Clonality:
Immunogen: Recombinant protein of human EIF2AK3
Clone #:
Conjugation: Unconjugated
Swissprot: Q9NZJ5
Santa Cruz:
Calculated MW: 125 kDa
Observed MW: 160 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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