Epigenetics & Nuclear Signaling Research

ERG Polyclonal Antibody | G-AB-00535 | Gentaur AntibodiesOverview: This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell...

GAS7 Polyclonal Antibody | G-AB-00528 | Gentaur AntibodiesOverview: Growth arrest-specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 plays a putative role in neuronal...

GADD45 gamma Polyclonal Antibody | G-AB-00524 | Gentaur AntibodiesOverview: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein...

TBX20 Polyclonal Antibody | G-AB-00520 | Gentaur AntibodiesOverview: This gene encodes a T-box family member. The T-box family members share a common DNA binding domain, termed the T-box, and they are transcription factors involved in the regulation of...

FGFR1 Polyclonal Antibody | G-AB-00519 | Gentaur AntibodiesOverview: The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout...

FANCF Polyclonal Antibody | G-AB-00518 | Gentaur AntibodiesOverview: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2) , FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1) ,...

ELAVL1 Polyclonal Antibody | G-AB-00508 | Gentaur AntibodiesOverview: The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found...

EGR1 Polyclonal Antibody | G-AB-00506 | Gentaur AntibodiesOverview: EGR-1 (Early growth response protein 1) also known as Zif268 (zinc finger protein 225) or NGFI-A (nerve growth factor-induced protein A) is a protein that in humans is encoded by the...

E2F6 Polyclonal Antibody | G-AB-00503 | Gentaur AntibodiesOverview: This gene encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. The protein encoded by this gene lacks the transactivation and...

E2F2 Polyclonal Antibody | G-AB-00502 | Gentaur AntibodiesOverview: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor...

DNMT3A Polyclonal Antibody | G-AB-00499 | Gentaur AntibodiesOverview: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA...

CREB1 Polyclonal Antibody | G-AB-00489 | Gentaur AntibodiesOverview: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an...

CRP Polyclonal Antibody | G-AB-00488 | Gentaur AntibodiesOverview: The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged...

c-Fos Polyclonal Antibody | G-AB-00481 | Gentaur AntibodiesOverview: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the...

CEBP epsilon Polyclonal Antibody | G-AB-00479 | Gentaur AntibodiesOverview: The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related...

BRCA1 Polyclonal Antibody | G-AB-00467 | Gentaur AntibodiesOverview: This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor...

BMPR1B Polyclonal Antibody | G-AB-00466 | Gentaur AntibodiesOverview: This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members...

CREB2 Polyclonal Antibody | G-AB-00463 | Gentaur AntibodiesOverview: This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR...

TRIM29 Polyclonal Antibody | G-AB-00459 | Gentaur AntibodiesOverview: The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers...

APEX1 Polyclonal Antibody | G-AB-00448 | Gentaur AntibodiesOverview: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites...

AIFM1 Polyclonal Antibody | G-AB-00443 | Gentaur AntibodiesOverview: This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis...

ABL1 Polyclonal Antibody | G-AB-00441 | Gentaur AntibodiesOverview: The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress...

AARS2 Polyclonal Antibody | G-AB-00439 | Gentaur AntibodiesOverview: The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with...

TONSL Polyclonal Antibody | G-AB-00431 | Gentaur AntibodiesOverview: The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the...

NFKBID Polyclonal Antibody | G-AB-00430 | Gentaur AntibodiesOverview: May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate...

CREB1 Polyclonal Antibody | G-AB-00419 | Gentaur AntibodiesOverview: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an...

STAT6 Polyclonal Antibody | G-AB-00418 | Gentaur AntibodiesOverview: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the...

RARB Polyclonal Antibody | G-AB-00397 | Gentaur AntibodiesOverview: This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the...

PKM Polyclonal Antibody | G-AB-00396 | Gentaur AntibodiesOverview: This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating...

ABL1 Polyclonal Antibody | G-AB-00380 | Gentaur AntibodiesOverview: The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress...

UBC Polyclonal Antibody | G-AB-00378 | Gentaur AntibodiesOverview: This gene represents a ubiquitin gene, ubiquitin C. The encoded protein is a polyubiquitin precursor. Conjugation of ubiquitin monomers or polymers can lead to various effects within a...

PCNA Polyclonal Antibody | G-AB-00355 | Gentaur AntibodiesOverview: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation...

HRAS Polyclonal Antibody | G-AB-00348 | Gentaur AntibodiesOverview: This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in...

Galectin 3 Polyclonal Antibody | G-AB-00339 | Gentaur AntibodiesOverview: Galectins are a family of animal lectins defined by shared characteristic amino-acid sequences and affinity for β-galactose-containing oligosac-charides . Galectin-3 contains one...

BMI1 Polyclonal Antibody | G-AB-00338 | Gentaur AntibodiesOverview: BMI- 1 is one of polycomb group genes, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit. Bmi1 plays an important role in the...

PDCD4 Polyclonal Antibody | G-AB-00297 | Gentaur AntibodiesOverview: Programmed cell death 4 (Pdcd4) is a novel tumor suppressor that inhibits translation, progression and invasion. It was first identified as being differnetially upregulated during...

DNMT1 Polyclonal Antibody | G-AB-00291 | Gentaur AntibodiesOverview: DNA (cytosine-5-) -methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are...

DNMT1 Polyclonal Antibody | G-AB-00290 | Gentaur AntibodiesOverview: DNA (cytosine-5-) -methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are...

c-SRC Polyclonal Antibody | G-AB-00288 | Gentaur AntibodiesOverview: SRC, also named as SRC1 and p60-Src, belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. It is a non-receptor protein tyrosine kinase that plays...

IFNAR1 Polyclonal Antibody | G-AB-00277 | Gentaur AntibodiesOverview: IFNAR1 (Interferon Alpha And Beta Receptor Subunit 1) is a Protein Coding gene. Diseases associated with IFNAR1 include Septicemic Plague and Hepatitis C. Among its related pathways...

IFNAR1 Polyclonal Antibody | G-AB-00276 | Gentaur AntibodiesOverview: IFNAR1 (Interferon Alpha And Beta Receptor Subunit 1) is a Protein Coding gene. Diseases associated with IFNAR1 include Septicemic Plague and Hepatitis C. Among its related pathways...

RBM3 Polyclonal Antibody | G-AB-00274 | Gentaur AntibodiesOverview: RBM3, also named as RNPL, is a cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures. It reduces the relative...

NF2 Polyclonal Antibody | G-AB-00273 | Gentaur AntibodiesOverview: This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the...

HMGB1 Polyclonal Antibody | G-AB-00272 | Gentaur AntibodiesOverview: High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA...

AKT1 Polyclonal Antibody | G-AB-00266 | Gentaur AntibodiesOverview: The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. Survival factors can suppress apoptosis in a...

NFATC4 Polyclonal Antibody | G-AB-00265 | Gentaur AntibodiesOverview: The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting...

EIF4EBP1 Polyclonal Antibody | G-AB-00264 | Gentaur AntibodiesOverview: Eukaryotic translation initiation factor 4E-binding protein 1 (4EBP1) , is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for...

Cyclin A2 Polyclonal Antibody | G-AB-00263 | Gentaur AntibodiesOverview: CCNA2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as...

NFκB-p65 Polyclonal Antibody | G-AB-00262 | Gentaur AntibodiesOverview: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of...

BRCA2 Polyclonal Antibody | G-AB-00259 | Gentaur AntibodiesOverview: Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome...

PTEN Polyclonal Antibody | G-AB-00243 | Gentaur AntibodiesOverview: PTEN (also designated MMAC1) , products of tumor suppressor genes, are found deleted in most human gliomas. The PTEN genes are also mutated in many other tumors, such as brain, breast,...

BRCA1 Polyclonal Antibody | G-AB-00241 | Gentaur AntibodiesOverview: RCA1, also named as RNF53, plays a central role in DNA repair by facilitating cellular response to DNA repair. It is required for appropriate cell cycle arrests after ionizing...

CRP Polyclonal Antibody | G-AB-00236 | Gentaur AntibodiesOverview: C-reactive protein (CRP) is an acute-phase serum protein synthesized by the liver in response to interleukin-6 (IL-6) during inflammation. The name of CRP derives from its ability to...

AK6 Polyclonal Antibody | G-AB-00226 | Gentaur AntibodiesOverview: This gene encodes a protein that belongs to the adenylate kinase family of enzymes. The protein has a nuclear localization and contains Walker A (P-loop) and Walker B motifs and a...

p16 Polyclonal Antibody | G-AB-00224 | Gentaur AntibodiesOverview: This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of...

RUNX2 Polyclonal Antibody | G-AB-00222 | Gentaur AntibodiesOverview: This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic...

CBX5 Polyclonal Antibody | G-AB-00221 | Gentaur AntibodiesOverview: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with...

HMG20B Polyclonal Antibody | G-AB-00218 | Gentaur AntibodiesOverview: HMG20B (High Mobility Group 20B) is a Protein Coding gene. Among its related pathways areResponse to elevated platelet cytosolic Ca2+andActivated PKN1 stimulates transcription of AR...

AIFM1 Polyclonal Antibody | G-AB-00215 | Gentaur AntibodiesOverview: This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis...

RAN Polyclonal Antibody | G-AB-00212 | Gentaur AntibodiesOverview: RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore...

PKM Polyclonal Antibody | G-AB-00211 | Gentaur AntibodiesOverview: PKM2, also named as OIP3, PK2, PK3, PKM, p58, THBP1, CTHBP and Tumor M2-PK, belongs to the pyruvate kinase family. It is glycolytic enzyme that catalyzes the transfer of a phosphoryl...

ATXN3 Polyclonal Antibody | G-AB-00206 | Gentaur AntibodiesOverview: Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG) n repeats in the coding...

RPLP1 Polyclonal Antibody | G-AB-00204 | Gentaur AntibodiesOverview: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and...

TRIM37 Polyclonal Antibody | G-AB-00198 | Gentaur AntibodiesOverview: This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM...

MEF2C Polyclonal Antibody | G-AB-00196 | Gentaur AntibodiesOverview: This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both...

CDC46 Polyclonal Antibody | G-AB-00194 | Gentaur AntibodiesOverview: The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a...

MCM7 Polyclonal Antibody | G-AB-00191 | Gentaur AntibodiesOverview: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The...

MCM3 Polyclonal Antibody | G-AB-00190 | Gentaur AntibodiesOverview: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The...

S100B Polyclonal Antibody | G-AB-00185 | Gentaur AntibodiesOverview: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a...

HOXA1 Polyclonal Antibody | G-AB-00184 | Gentaur AntibodiesOverview: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these...

EEF2 Polyclonal Antibody | G-AB-00179 | Gentaur AntibodiesOverview: This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation...

NR1H3 Polyclonal Antibody | G-AB-00178 | Gentaur AntibodiesOverview: The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling...

SF3B3 Polyclonal Antibody | G-AB-00173 | Gentaur AntibodiesOverview: This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear...

IMP3 Polyclonal Antibody | G-AB-00171 | Gentaur AntibodiesOverview: This gene encodes the human homolog of the yeast Imp3 protein. The protein localizes to the nucleoli and interacts with the U3 snoRNP complex. The protein contains an S4 domain. IMP3...

HMGB2 Polyclonal Antibody | G-AB-00162 | Gentaur AntibodiesOverview: This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the...

C15orf23 Polyclonal Antibody | G-AB-00156 | Gentaur AntibodiesOverview: Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase . Promotes the metaphase-to-anaphase transition and is required...

SF3A3 Polyclonal Antibody | G-AB-00154 | Gentaur AntibodiesOverview: This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of...

EIF5A2 Polyclonal Antibody | G-AB-00151 | Gentaur AntibodiesOverview: EIF5A2 (Eukaryotic Translation Initiation Factor 5A2) is a Protein Coding gene. Among its related pathways areGamma carboxylation, hypusine formation and arylsulfatase...

SIX2 Polyclonal Antibody | G-AB-00150 | Gentaur AntibodiesOverview: This gene is a member of the vertebrate gene family which encode proteins homologous to the Drosophila 'sine oculis' homeobox protein. The encoded protein is a transcription factor...

THRAP3 Polyclonal Antibody | G-AB-00148 | Gentaur AntibodiesOverview: THRAP3 (Thyroid Hormone Receptor Associated Protein 3) is a Protein Coding gene. Among its related pathways arePEDF Induced SignalingandCircadian rythm related genes. GO annotations...

SIX1 Polyclonal Antibody | G-AB-00146 | Gentaur AntibodiesOverview: The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and...

EGR2 Polyclonal Antibody | G-AB-00137 | Gentaur AntibodiesOverview: The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D)...

STAT2 Polyclonal Antibody | G-AB-00131 | Gentaur AntibodiesOverview: Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta) . Following type I IFN binding to cell surface receptors, Jak kinases...

BAP1 Polyclonal Antibody | G-AB-00129 | Gentaur AntibodiesOverview: Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A and HCFC1. Catalytic component of the PR-DUB complex, a complex that specifically...

P73 Polyclonal Antibody | G-AB-00126 | Gentaur AntibodiesOverview: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the...

IGF2BP2 Polyclonal Antibody | G-AB-00117 | Gentaur AntibodiesOverview: RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs) . This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It...

IkB alpha Polyclonal Antibody | G-AB-00111 | Gentaur AntibodiesOverview: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by...

SOX-2 Polyclonal Antibody | G-AB-00100 | Gentaur AntibodiesOverview: Sox2, also known as SRY (sex determining region Y) -box 2, is a transcription factor essential for maintaining self-renewal of undifferentiated ES cells and is one of the key...

RPS25 Polyclonal Antibody | G-AB-00088 | Gentaur AntibodiesOverview: ibosomal protein S25 (RPS25) is a novel MDM2 interacting protein. It may be involved in viral replication of Dicistroviridae and hepatitis C viruses. RPS25 is overexpressed in human...

KRAS Polyclonal Antibody | G-AB-00085 | Gentaur AntibodiesOverview: KRAS, also called p21, is a member of the Ras superfamily of proteins. It is located on human chromosome 12, and contains four coding exons and a 5' non-coding exon (PMID: 12778136) ...

TUFM Polyclonal Antibody | G-AB-00080 | Gentaur AntibodiesOverview: TUFM, also named as Elongation factor Tu, mitochondrial, is a 452 amino acid protein, which contains 1 tr-type G (guanine nucleotide-binding) domain and belongs to the TRAFAC class...

TRIP4 Polyclonal Antibody | G-AB-00075 | Gentaur AntibodiesOverview: This gene encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC-1) complex, which associates with transcriptional coactivators, nuclear receptors and basal...

STK4 Polyclonal Antibody | G-AB-00073 | Gentaur AntibodiesOverview: The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein...

MGMT Polyclonal Antibody | G-AB-00072 | Gentaur AntibodiesOverview: Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense...

IRF3 Polyclonal Antibody | G-AB-00071 | Gentaur AntibodiesOverview: This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine...

CDC40 Polyclonal Antibody | G-AB-00067 | Gentaur AntibodiesOverview: Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing.Category Type: Polyclonal AntibodyResearch Areas: Cancer, Cell...

ILF2 Polyclonal Antibody | G-AB-00066 | Gentaur AntibodiesOverview: Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the...

STAT3 Polyclonal Antibody | G-AB-00065 | Gentaur AntibodiesOverview: Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as...

PARP3 Polyclonal Antibody | G-AB-00062 | Gentaur AntibodiesOverview: Involved in the base excision repair (BER) pathway, by catalyzing the poly (ADP-ribosyl) ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA...

P21 Polyclonal Antibody | G-AB-00054 | Gentaur AntibodiesOverview: May be involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of...