ESPL1 Polyclonal Antibody | G-AB-01683

ESPL1 Polyclonal Antibody | G-AB-01683 | Gentaur Antibodies

Overview: Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 or STAG2 in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 by ESPL1, or separase, which initiates the final separation of sister chromatids.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms: Caspase like protein ESPL1, Caspase-like protein ESPL1, ESP 1, ESP1, ESPL 1, Espl1, ESPL1, Extra spindle poles like 1, Extra spindle poles like 1 protein, Extra spindle poles-like 1 protein, FLJ46492, KIAA0165, Separase, Separin, Similar to fission yeast cut1and gene, SSE

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_036423

Clonality: Polyclonal

Immunogen: Synthetic peptide of human ESPL1

Clone #:

Conjugation: Unconjugated

Swissprot: Q14674

Santa Cruz: sc-27217/sc-27219/sc-25839

Calculated MW: 233 kDa

Observed MW:

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:200-1:1000, IHC 1:25-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ESPL1 Polyclonal Antibody DataSheet