EWSR1 Polyclonal Antibody | G-AB-04403

EWSR1 Polyclonal Antibody | G-AB-04403 | Gentaur Antibodies

Overview: This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t (11;22) (q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Tags & Cell Markers

Synonyms: bK984G1.4, bK984G1.4 Ewing sarcoma breakpoint region 1 protein, Ewing sarcoma breakpoint region 1, Ewing sarcoma breakpoint region 1 protein, Ewings sarcoma EWS Fli1 type 1 oncogene, EWS, EWS oncogene, EWS RNA binding protein 1, EWS, EWSR 1, Ewsr1, EWSR1 protein, RNA binding protein EWS, RNA-binding protein EWS

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC000527

Clonality: Polyclonal

Immunogen: Fusion protein of human EWSR1

Clone #:

Conjugation: Unconjugated

Swissprot: Q01844

Santa Cruz:

Calculated MW: 68 kDa

Observed MW: Refer to figures

Concentration: 1.26 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

EWSR1 Polyclonal Antibody DataSheet