EZH2 Polyclonal Antibody | G-AB-05281

EZH2 Polyclonal Antibody | G-AB-05281 | Gentaur Antibodies

Overview: EZH2 (enhancer of zeste homologue 2, also known as KMT6) is a member of Polycomb group (PcG) family and encodes a histone methyl transferase that has an essential role in promoting histone H3 lysine 27 trimethylation (H3K27me3) and epigenetic gene silencing. EZH2 is important for cell proliferation and inhibition of cell differentiation, and is implicated in cancer progression. Overexpression of EZH2 is a marker of advanced and metastatic disease in many solid tumors, including prostate and breast cancer. This antibody detected EZH2 protein as a single band with a molecular weight (MW) of 91-100 kDa in multiple cell lines. The phosphorylation may result in the higher molecular weight (calculated MW as 80-86 kDa) . (20935635, 21367748)

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: Enhancer of zeste 2, enhancer of zeste 2 polycomb repressive complex 2 subunit, Enhancer of zeste homolog 2 (Drosophila) , Enhancer of zeste homolog 2, Enhancer of zeste, Drosophila, homolog 2, ENX 1, Enx 1h, ENX-1, ENX1, Enx1h, EZH 2, EZH1, EZH2, EZH2, EZH2b, Histone-lysine N-methyltransferase EZH2, KMT 6, KMT6, KMT6A, Lysine N-methyltransferase 6, MGC9169, WVS, WVS2

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse EZH2

Clone #:

Conjugation: Unconjugated

Swissprot: Q15910, Q61188

Santa Cruz:

Calculated MW: 80-100 kDa

Observed MW: 80 kDa

Concentration: 0.54 mg/mL

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

EZH2 Polyclonal Antibody DataSheet