FBLN5 Polyclonal Antibody | G-AB-12456

FBLN5 Polyclonal Antibody | G-AB-12456 | Gentaur Antibodies

Overview: The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I) , and age-related macular degeneration type 3 (ARMD3) .

Category Type: Polyclonal Antibody

Research Areas: Cardiovascular, Signal Transduction

Synonyms: FBLN5, ADCL2, ARCL1A, ARMD3, DANCE, EVEC, FIBL-5, HNARMD, UP50, fibulin-5

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 10516

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human FBLN5 (NP_006320.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9UBX5

Santa Cruz:

Calculated MW: 50 kDa

Observed MW: 72 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

FBLN5 Polyclonal Antibody DataSheet