FGB Polyclonal Antibody | G-AB-00346

FGB Polyclonal Antibody | G-AB-00346 | Gentaur Antibodies

Overview: The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.

Category Type: Polyclonal Antibody

Research Areas: Cardiovascular, Metabolism

Synonyms: Beta fibrinogen, Epididymis Secretory Sperm Binding Protein Li 78p, FGB, Fibrinogen beta chain, HEL-S-78p

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 2244

Accession #:

Clonality: Polyclonal

Immunogen: Recombinant Human Fibrinogen beta chain protein

Clone #:

Conjugation: Unconjugated

Swissprot: P02675

Santa Cruz:

Calculated MW: 55 kDa

Observed MW: 55 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3

Purification method: Antigen Affinity Purification

Application: WB, IHC

Dilution: WB 1:2000-1:4000 IHC 1:100-1:300

Storage: Store at -20°C. Avoid freeze / thaw cycles.

FGB Polyclonal Antibody DataSheet