GLP1R Polyclonal Antibody | G-AB-12262
- 3 to 5 Working Days
- Mouse, Rat
GLP1R Polyclonal Antibody | G-AB-12262 | Gentaur Antibodies
Overview: This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants.
Category Type: Polyclonal Antibody
Research Areas: Cardiovascular, Neuroscience
Synonyms: GLP1R, GLP-1, GLP-1-R, GLP-1R
Reactivity: Mouse, Rat
Gene ID: 2740
Immunogen: Recombinant fusion protein of human GLP1R (NP_002053.3) .
Calculated MW: 53 kDa
Observed MW: 53 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.