GLP1R Polyclonal Antibody | G-AB-12262

GLP1R Polyclonal Antibody | G-AB-12262 | Gentaur Antibodies

Overview: This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cardiovascular, Neuroscience

Synonyms: GLP1R, GLP-1, GLP-1-R, GLP-1R

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 2740

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human GLP1R (NP_002053.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: P43220

Santa Cruz:

Calculated MW: 53 kDa

Observed MW: 53 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

GLP1R Polyclonal Antibody DataSheet