GMNN Polyclonal Antibody | G-AB-10590

GMNN Polyclonal Antibody | G-AB-10590 | Gentaur Antibodies

Overview: This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: GMNN, Gem, MGORS6, geminin

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 51053

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human GMNN (NP_056979.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O75496

Santa Cruz:

Calculated MW: 23 kDa

Observed MW: 24 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

GMNN Polyclonal Antibody DataSheet