HGF Polyclonal Antibody | G-AB-00537

HGF Polyclonal Antibody | G-AB-00537 | Gentaur Antibodies

Overview: Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: DFNB39, F TCF, Fibroblast derived tumor cytotoxic factor, Hepatocyte growth factor (hepapoietin A, scatter factor) , Hepatocyte growth factor, Hepatocyte growth factor beta chain, Hepatocyte growth factor precursor, Hepatopoietin A, Hepatopoietin-A, Hgf, HGF, HGFB, HPTA, Lung fibroblast derived mitogen, OTTHUMP00000161349, OTTHUMP00000206710, OTTHUMP00000206711, OTTHUMP00000206712, OTTHUMP00000206713, OTTHUMP00000206730, Scatter factor, SF

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC063485

Clonality: Polyclonal

Immunogen: Recombinant protein of human HGF

Clone #:

Conjugation: Unconjugated

Swissprot: P14210

Santa Cruz: sc-1357/sc-1356/sc-34462/sc-34461/sc-1358/sc-7949/sc-13087

Calculated MW:

Observed MW:

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

HGF Polyclonal Antibody DataSheet