Histone H2B Monoclonal Antibody | G-AB-05574
- 3 to 5 Working Days
- Human, Mouse, Rat
Histone H2B Monoclonal Antibody | G-AB-05574 | Gentaur Antibodies
Overview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. HIST1H2BB (Histone Cluster 1 H2B Family Member B) is a Protein Coding gene. Among its related pathways are DNA Double-Strand Break Repair and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. GO annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is HIST1H2BN.
Category Type: Monoclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Synonyms: HIST1H2BA, testis, bA317E16.3, H2B, H2B histone family member U, H2B histone family member U testis specific, H2B histone family, member U, (testis specific) , H2B testis, H2B1A, H2BFU, H2BT, HIST1H2BA, Histone 1, H2ba, Histone cluster 1 H2ba, Histone H2B, Histone H2B testis, Histone H2B type 1 A, Histone H2B type 1-A, Histone H2B type 1A, STBP, Testis specific histone H2B, Testis-specific histone H2B, TSH 2B, TSH2B, TSH2B.1
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic Peptide
Clone #: Clone:3C3
Calculated MW: 14 kDa
Observed MW: 14 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification method: Protein A purification
Application: WB, IF
Dilution: WB 1:1000-3000, IF 1:100-200
Storage: Store at -20°C. Avoid freeze / thaw cycles.