HRG Polyclonal Antibody | G-AB-12197
- 3 to 5 Working Days
- Mouse, Rat
HRG Polyclonal Antibody | G-AB-12197 | Gentaur Antibodies
Overview: This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. The encoded protein also has a peptide that displays antimicrobial activity against C. albicans, E. coli, S. aureus, P. aeruginosa, and E. faecalis. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.
Category Type: Polyclonal Antibody
Research Areas: Cardiovascular
Synonyms: HRG, HPRG, HRGP, THPH11
Reactivity: Mouse, Rat
Gene ID: 3273
Immunogen: Recombinant fusion protein of human HRG (NP_000403.1) .
Calculated MW: 59 kDa
Observed MW: 80 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IHC
Dilution: WB 1:500-1:2000 IHC 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.