HRG Polyclonal Antibody | G-AB-12197

HRG Polyclonal Antibody | G-AB-12197 | Gentaur Antibodies

Overview: This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. The encoded protein also has a peptide that displays antimicrobial activity against C. albicans, E. coli, S. aureus, P. aeruginosa, and E. faecalis. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.

Category Type: Polyclonal Antibody

Research Areas: Cardiovascular

Synonyms: HRG, HPRG, HRGP, THPH11

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 3273

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human HRG (NP_000403.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P04196

Santa Cruz:

Calculated MW: 59 kDa

Observed MW: 80 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

HRG Polyclonal Antibody DataSheet