Icam5 Polyclonal Antibody | G-AB-09167

Icam5 Polyclonal Antibody | G-AB-09167 | Gentaur Antibodies

Overview: ICAM-5, also known as telencephalin, is a type I integral membrane glycoprotein of the immunoglobulin superfamily. It is specifically expressed in the postnatal excitatory neuronal cell bodies, dendritic shafts, and dendritic filopodia of the telencephalon. ICAM-5 functions in both the immune and nervous systems. ICAM-5 strongly stimulates neurite outgrowth. It is cleaved by matrix metalloproteases upon activation of glutamate receptors or degraded through endocytosis resulting in increased spine maturation. The cleaved soluble fragment of ICAM-5 is immunosuppressive, which may be important in neuronal inflammatory diseases.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: ICAM5, TLCN, TLN, Icam5

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 15898

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of mouse Icam5 (NP_032345.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q60625

Santa Cruz:

Calculated MW: 96 kDa

Observed MW: 140 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Icam5 Polyclonal Antibody DataSheet