IFITM3 Polyclonal Antibody | G-AB-00223
- 3 to 5 Working Days
- Human, Mouse, Rat
IFITM3 Polyclonal Antibody | G-AB-00223 | Gentaur Antibodies
Overview: IFITM3, also named as interferon-inducible protein 1-8U, belongs to the CD225 family. It is IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV) , and dengue virus, by inhibiting the early steps of replication. IFITM3 is identified as interferon-induced cellular proteins that restrict infections by retroviruses and filoviruses and of influenza virus and flaviviruses, respectively. IFITM3, the most potent antiviral IFITM, was found to inhibit an uncharacterized early infectious event after VSV endocytosis, but before primary transcription of its viral genome. IFITM proteins are viral restriction factors that can inhibit infection mediated by the influenza A virus (IAV) hemagglutinin (HA) protein. They differentially restrict the entry of a broad range of enveloped viruses, and modulate cellular tropism independently of viral receptor expression. This antibody recognizes both IFITM2 and IFITM3.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Developmental Biology, Stem Cells
Synonyms: 1 8U, Fragilis, IFITM3, IFM3, Interferon induced transmembrane protein 3 (1 8U) , Interferon Induced Transmembrane Protein 3, Interferon inducible, Interferon inducible protein 1 8U, Interferon Inducible Protein 15, Interferon Inducible Protein Homolog, Interferon-induced transmembrane protein 3, Interferon-inducible protein 1-8U, IP15
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant Rat Interferon-induced transmembrane protein 3 protein
Calculated MW: 15 kDa
Observed MW: 15 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Purification method: Antigen Affinity Purification
Application: WB, IHC, IF
Dilution: WB 1:1000-1:2000 IHC 1:50-1:200 IF 1:100-1:400
Storage: Store at -20°C. Avoid freeze / thaw cycles.