IL21R Polyclonal Antibody | G-AB-11704

IL21R Polyclonal Antibody | G-AB-11704 | Gentaur Antibodies

Overview: The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21) . It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology

Synonyms: IL21R, CD360, NILR

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 50615

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human IL21R (NP_851565.4) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9HBE5

Santa Cruz:

Calculated MW: 59 kDa

Observed MW: 70 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

IL21R Polyclonal Antibody DataSheet