IL27 Polyclonal Antibody | G-AB-00177

IL27 Polyclonal Antibody | G-AB-00177 | Gentaur Antibodies

Overview: IL-27, a member of IL-12/IL-23 heterodimeric family of cytokines, has pleiotropic properties that can enhance or limit immune responses. IL-27 is a heterodimeric cytokine composed of two subunits: IL-27a and IL-27b. IL-27 acts on various cell types, including T cells, B cells, macrophages, dendritic cells, natural killer (NK) cells and non-hematopoietic cells. IL-27 plays a critical role in the early regulation of T helper type 1 initiation, and enhances proliferation of naive CD4+T cells and naive B cells. It, however, also exerts anti-inflammatory functions by inhibiting the development of Th17 cells and inducing IL-10 producing type 1 regulatory T cells. IL-27 is a potentially promising cytokine for therapeutic approaches on various human diseases.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology

Synonyms: EBI3, IL 27, IL 27 p28 subunit, IL 27A, IL 30, IL-27 subunit alpha, IL-27-A, IL27, IL27-A, IL27A, IL27A_HUMAN, IL27p28, IL30, Interleukin 27, Interleukin 27 subunit alpha

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: Recombinant Human Interleukin-27 subunit alpha protien

Clone #:

Conjugation: Unconjugated

Swissprot: Q8NEV9

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 2 mg/mL

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:100-1:400

Storage: Store at -20°C. Avoid freeze / thaw cycles.

IL27 Polyclonal Antibody DataSheet