IL5 Polyclonal Antibody | G-AB-11811
- 3 to 5 Working Days
- Human, Mouse, Rat
IL5 Polyclonal Antibody | G-AB-11811 | Gentaur Antibodies
Overview: This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF) . This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4) , interleukin 13 (IL13) , and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Immunology
Synonyms: IL5, EDF, IL-5, TRF
Reactivity: Human, Mouse, Rat
Gene ID: 3567
Immunogen: Recombinant fusion protein of human IL5 (NP_000870.1) .
Calculated MW: 15 kDa
Observed MW: 13 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IHC
Dilution: WB 1:500-1:2000 IHC 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.