IL5 Polyclonal Antibody | G-AB-11811

IL5 Polyclonal Antibody | G-AB-11811 | Gentaur Antibodies

Overview: This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF) . This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4) , interleukin 13 (IL13) , and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology

Synonyms: IL5, EDF, IL-5, TRF

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 3567

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human IL5 (NP_000870.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P05113

Santa Cruz:

Calculated MW: 15 kDa

Observed MW: 13 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

IL5 Polyclonal Antibody DataSheet