Insulin Receptor Polyclonal Antibody | G-AB-07172
Gentaur Antibodies
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Gentaur Antibodies
Insulin Receptor Polyclonal Antibody | G-AB-07172
- SKU:
- G-AB-07172
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Mouse, Rat
Insulin Receptor Polyclonal Antibody | G-AB-07172 | Gentaur Antibodies
Overview: This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction
Synonyms: CD220, HHF5, INSR
Reactivity: Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 3643
Accession #:
Clonality:
Immunogen: A synthetic peptide of human Insulin Receptor (NP_000199.2) .
Clone #:
Conjugation: Unconjugated
Swissprot: P06213
Santa Cruz:
Calculated MW: 155 kDa/156 kDa
Observed MW: 180 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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