Insulin Receptor Polyclonal Antibody | G-AB-07172

Insulin Receptor Polyclonal Antibody | G-AB-07172 | Gentaur Antibodies

Overview: This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction

Synonyms: CD220, HHF5, INSR

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 3643

Accession #:

Clonality:

Immunogen: A synthetic peptide of human Insulin Receptor (NP_000199.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P06213

Santa Cruz:

Calculated MW: 155 kDa/156 kDa

Observed MW: 180 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Insulin Receptor Polyclonal Antibody DataSheet