ITM2B Polyclonal Antibody | G-AB-06344

ITM2B Polyclonal Antibody | G-AB-06344 | Gentaur Antibodies

Overview: Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.

Category Type: Polyclonal Antibody

Research Areas: Neuroscience

Synonyms: ABRI, ABri/ADan amyloid peptide, BRI 2, BRI, BRI2, BRICD 2B, BRICD2B, BRICHOS domain containing 2B, E25B, E3 16, E3-16, FBD, imBRI2, Immature BRI2, Integral membrane protein 2B, ITM 2B, ITM2B, ITM2B, Protein E25B, RDGCA, Transmembrane protein BRI

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC000554

Clonality: Polyclonal

Immunogen: Fusion protein of human ITM2B

Clone #:

Conjugation: Unconjugated

Swissprot: Q9Y287

Santa Cruz:

Calculated MW: 30 kDa

Observed MW: Refer to figures

Concentration: 0.96 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: WB, ELISA

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ITM2B Polyclonal Antibody DataSheet