(KO Validated) BAX Polyclonal Antibody | G-AB-07672

(KO Validated) BAX Polyclonal Antibody | G-AB-07672 | Gentaur Antibodies

Overview: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC) , which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Metabolism

Synonyms: BCL2L4, BAX

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 581

Accession #:

Clonality:

Immunogen: A synthetic peptide of human BAX (NP_620116.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q07812

Santa Cruz:

Calculated MW: 4 kDa/12 kDa/15 kDa/18 kDa/19 kDa/21 kDa/24 kDa

Observed MW: 20 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:100-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

(KO Validated) BAX Polyclonal Antibody DataSheet