(KO Validated) DNMT1 Polyclonal Antibody | G-AB-10690
- 3 to 5 Working Days
(KO Validated) DNMT1 Polyclonal Antibody | G-AB-10690 | Gentaur Antibodies
Overview: This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Synonyms: ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT, m.HsaI, DNMT1
Gene ID: 1786
Immunogen: Recombinant fusion protein of human DNMT1 (NP_001370.1) .
Calculated MW: 144 kDa/183 kDa/184 kDa
Observed MW: 200 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IF
Dilution: WB 1:500-1:2000 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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The delivery was very quick and on time that I was surprised by the very effective service. Thanks, Gentaur!