(KO Validated) LITAF Polyclonal Antibody | G-AB-10673

(KO Validated) LITAF Polyclonal Antibody | G-AB-10673 | Gentaur Antibodies

Overview: Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD) . Multiple alternatively spliced transcript variants have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms: LITAF, PIG7, SIMPLE, TP53I7

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 9516

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human LITAF (NP_004853.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q99732

Santa Cruz:

Calculated MW: 15 kDa/17 kDa/23 kDa

Observed MW: 20 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

(KO Validated) LITAF Polyclonal Antibody DataSheet