(KO Validated) SQSTM1 / p62 Polyclonal Antibody | G-AB-07560

(KO Validated) SQSTM1 / p62 Polyclonal Antibody | G-AB-07560 | Gentaur Antibodies

Overview: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction

Synonyms: SQSTM1, A170, DMRV, FTDALS3, NADGP, OSIL, PDB3, ZIP3, p60, p62, p62B

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 8878

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human SQSTM1 / p62 (NP_001135770.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q13501

Santa Cruz:

Calculated MW: 38 kDa/47 kDa

Observed MW: 62 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

(KO Validated) SQSTM1 / p62 Polyclonal Antibody DataSheet