Lamin A/C Polyclonal Antibody
Lamin A/C Polyclonal Antibody
Western blot analysis of extracts of various cell lines using Lamin A/C Polyclonal Antibody at dilution of 1:1000. HeLa cells were treated by Hydroxyurea (4 mM) at 37°C for 20 hours or treated by Paclitaxel (100 nM/ml) at 37°C for 20 hours. C6 cells were treated by Hydroxyurea (4 mM) at 37°C for 20 hours or treated by Paclitaxel (100 nM) at 37°C for 20 hours.
Immunohistochemistry of paraffin-embedded Rat brain using Lamin A/C Polyclonal Antibody at dilution of 1:200 (40x lens) .
Immunohistochemistry of paraffin-embedded Mouse kidney using Lamin A/C Polyclonal Antibody at dilution of 1:200 (40x lens) .
Immunohistochemistry of paraffin-embedded Human gastric cancer using Lamin A/C Polyclonal Antibody at dilution of 1:100 (40x lens) .
Confocal immunofluorescence analysis of A-431 cells using Lamin A/C Polyclonal Antibody at dilution of 1:200. Blue: DAPI for nuclear staining.
Confocal immunofluorescence analysis of HeLa cells using Lamin A/C Polyclonal Antibody at dilution of 1:200. Blue: DAPI for nuclear staining.
Confocal immunofluorescence analysis of U-2 OS cells using Lamin A/C Polyclonal Antibody at dilution of 1:200. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of HeLa cells using Lamin A/C Polyclonal Antibody

Lamin A/C Polyclonal Antibody | G-AB-07152

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$218.00 - $465.00
SKU:
G-AB-07152
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
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Lamin A/C Polyclonal Antibody | G-AB-07152 | Gentaur Antibodies

Overview: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction, Tags & Cell Markers

Synonyms: LMNA, CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, MADA, PRO1, lamin, Lamin A/C

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 4000

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human Lamin C (NP_005563.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P02545

Santa Cruz:

Calculated MW: 62-74 kDa

Observed MW: 69 kDa/72 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Lamin A/C Polyclonal Antibody DataSheet

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