Lamin B1 Polyclonal Antibody | G-AB-00217
- 3 to 5 Working Days
- Human, Rat, Mouse
Lamin B1 Polyclonal Antibody | G-AB-00217 | Gentaur Antibodies
Overview: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD) .
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Signal Transduction, Tags & Cell Markers
Synonyms: ADLD, lamin B1, Lamin-B1, LMN, LMN2, LMNB, Lmnb1, LMNB1, MGC111419, OTTHUMP00000159218
Reactivity: Human, Rat, Mouse
Immunogen: Recombinant Rat Lamin-B1 protein
Calculated MW: 67 kDa
Observed MW: 72 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Purification method: Antigen Affinity Purification
Application: WB, IHC, IF
Dilution: WB 1:1000-1:2000 IHC 1:100-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.