Lamin B1 Polyclonal Antibody | G-AB-05910

Lamin B1 Polyclonal Antibody | G-AB-05910 | Gentaur Antibodies

Overview: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD) .

Category Type: Control Antibody

Research Areas: Cancer, Cell Biology, Signal Transduction, Tags & Cell Markers

Synonyms: ADLD, lamin B1, Lamin-B1, LMN, LMN2, LMNB, Lmnb1, LMNB1, MGC111419, OTTHUMP00000159218

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from the N-terminal region of human Lamin B1.

Clone #:

Conjugation: Unconjugated

Swissprot: P20700

Santa Cruz:

Calculated MW: 66 kDa

Observed MW: 67 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification method: Affinity purification

Application: WB, IHC-p, IF, ELISA

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:40000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Lamin B1 Polyclonal Antibody DataSheet