MAP3K12 Polyclonal Antibody | G-AB-00655

MAP3K12 Polyclonal Antibody | G-AB-00655 | Gentaur Antibodies

Overview: This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: Dlk, Dual leucine zipper bearing kinase, Dual leucine zipper kinase DLK, Leucine-zipper protein kinase, M3K12, Map3k12, MAPK-upstream kinase, MEKK12, Mitogen-activated protein kinase kinase kinase 12, Mixed lineage kinase, MUK, Protein kinase MUK, ZPK, ZPKP1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC050050

Clonality: Polyclonal

Immunogen: Recombinant protein of human MAP3K12

Clone #:

Conjugation: Unconjugated

Swissprot: Q12852

Santa Cruz: sc-8125

Calculated MW:

Observed MW:

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:25-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MAP3K12 Polyclonal Antibody DataSheet