MAPKAPK3 Polyclonal Antibody | G-AB-04666

MAPKAPK3 Polyclonal Antibody | G-AB-04666 | Gentaur Antibodies

Overview: This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase) - activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs) , act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Alternate splicing results in multiple transcript variants that encode the same protein.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: 3pK, anti MAPKAPK3, Chromosome 3p kinase, EC 2.7.11.1, MAP kinase-activated protein kinase 3, MAPK activated protein kinase 3, MAPK-activated protein kinase 3, MAPK3, MAPKAP, MAPKAP kinase 3, MAPKAP-K3, MAPKAP3, MAPKAPK 3, MAPKAPK-3, Mapkapk3, MAPKAPK3, Mitogen activated protein kinase activated protein kinase 3, Mitogen activated protein kinase activated protein kinase, MK-3

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC001662

Clonality: Polyclonal

Immunogen: Fusion protein of human MAPKAPK3

Clone #:

Conjugation: Unconjugated

Swissprot: Q16644

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1.4 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:100-1:300, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MAPKAPK3 Polyclonal Antibody DataSheet