MKL1 Polyclonal Antibody | G-AB-12240
- 3 to 5 Working Days
- Human, Mouse, Rat
MKL1 Polyclonal Antibody | G-AB-12240 | Gentaur Antibodies
Overview: The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction, Stem Cells
Synonyms: MKL1, BSAC, MAL, MRTF-A
Reactivity: Human, Mouse, Rat
Gene ID: 57591
Immunogen: Recombinant fusion protein of human MKL1 (NP_065882.1) .
Calculated MW: 98 kDa
Observed MW: 145 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IHC, IF
Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.