MKL1 Polyclonal Antibody | G-AB-12240

MKL1 Polyclonal Antibody | G-AB-12240 | Gentaur Antibodies

Overview: The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction, Stem Cells

Synonyms: MKL1, BSAC, MAL, MRTF-A

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 57591

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human MKL1 (NP_065882.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q969V6

Santa Cruz:

Calculated MW: 98 kDa

Observed MW: 145 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MKL1 Polyclonal Antibody DataSheet