Mono-Methyl-P53 (Lys370) Monoclonal Antibody | G-AB-05835
- 3 to 5 Working Days
- Human, Mouse, Rat
Mono-Methyl-P53 (Lys370) Monoclonal Antibody | G-AB-05835 | Gentaur Antibodies
Overview: The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
Category Type: Methylated antibody
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling
Synonyms: Antigen NY-CO-13, BCC7, Cellular tumor antigen p53, FLJ92943, LFS1, Mutant tumor protein 53, p53, p53 tumor suppressor, P53, Phosphoprotein p53, Tp53, Transformation related protein 53, TRP53, Tumor protein 53, Tumor protein p53, Tumor suppressor p53
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic Peptide
Clone #: Clone:4A1
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification method: Protein A purification
Dilution: IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.