MYH7 Polyclonal Antibody | G-AB-11755
- 3 to 5 Working Days
- Mouse, Rat
MYH7 Polyclonal Antibody | G-AB-11755 | Gentaur Antibodies
Overview: Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Developmental Biology, Signal Transduction, Stem Cells
Synonyms: MYH7, CMD1S, CMH1, MPD1, MYHCB, SPMD, SPMM, myosin-7, MYH7
Reactivity: Mouse, Rat
Gene ID: 4625
Immunogen: Recombinant fusion protein of human MYH7 (NP_000248.2) .
Calculated MW: 223 kDa
Observed MW: 223 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IHC, IF
Dilution: WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.