MYH7 Polyclonal Antibody | G-AB-11755

MYH7 Polyclonal Antibody | G-AB-11755 | Gentaur Antibodies

Overview: Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Developmental Biology, Signal Transduction, Stem Cells

Synonyms: MYH7, CMD1S, CMH1, MPD1, MYHCB, SPMD, SPMM, myosin-7, MYH7

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 4625

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human MYH7 (NP_000248.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P12883

Santa Cruz:

Calculated MW: 223 kDa

Observed MW: 223 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MYH7 Polyclonal Antibody DataSheet