MYSM1 Polyclonal Antibody | G-AB-01440

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MYSM1 Polyclonal Antibody | G-AB-01440 | Gentaur Antibodies

Overview: Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR) -induced gene activation.Component of a large chromatin remodeling complex, at least composed of MYSM1, PCAF, RBM10 and KIF11/TRIP5. Binds histones

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: 2A-DUB, 2ADUB, Histone H2A deubiquitinase, Histone H2A deubiquitinase MYSM1, KIAA1915, Myb like SWIRM and MPN domains 1, Myb like, SWIRM and MPN domain containing protein, Myb like, SWIRM and MPN domains 1, Myb-like, Myb-like, SWIRM and MPN domains 1, MYSM 1, mysm1, MYSM1 Myb-like, SWIRM and MPN domains 1, MYSM1, RP4-592A1.1, SWIRM and MPN domain-containing protein 1

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_001078956

Clonality: Polyclonal

Immunogen: Synthetic peptide of human MYSM1

Clone #:

Conjugation: Unconjugated

Swissprot: Q5VVJ2

Santa Cruz: sc-161894/sc-161895

Calculated MW:

Observed MW:

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MYSM1 Polyclonal Antibody DataSheet