MYSM1 Polyclonal Antibody | G-AB-10269

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$218.00 - $465.00
SKU:
G-AB-10269
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
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MYSM1 Polyclonal Antibody | G-AB-10269 | Gentaur Antibodies

Overview: Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR) -induced gene activation.Component of a large chromatin remodeling complex, at least composed of MYSM1, PCAF, RBM10 and KIF11/TRIP5. Binds histones

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: MYSM1, 2A-DUB, 2ADUB

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 114803

Accession #:

Clonality:

Immunogen: A synthetic peptide of human MYSM1 (NP_001078956.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q5VVJ2

Santa Cruz:

Calculated MW: 26 kDa/66 kDa/95 kDa

Observed MW: 105 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MYSM1 Polyclonal Antibody DataSheet