NFkB p100 / p52 Polyclonal Antibody | G-AB-07496

NFkB p100 / p52 Polyclonal Antibody | G-AB-07496 | Gentaur Antibodies

Overview: This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB) . The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms: CVID10, H2TF1, LYT-10, LYT10, NF-kB2, p100, p49/p100, p52

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 4791

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human NFkB p100 / p52 (NP_002493.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q00653

Santa Cruz:

Calculated MW: 47 kDa/96 kDa

Observed MW: 125 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

NFkB p100 / p52 Polyclonal Antibody DataSheet