NPHP1 Polyclonal Antibody | G-AB-04514
Gentaur Antibodies
- SKU:
- G-AB-04514
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
NPHP1 Polyclonal Antibody | G-AB-04514 | Gentaur Antibodies
Overview: This gene encodes a protein with src homology domain 3 (SH3) patterns. This protein interacts with Crk-associated substrate, and it appears to function in the control of cell division, as well as in cell-cell and cell-matrix adhesion signaling, likely as part of a multifunctional complex localized in actin- and microtubule-based structures. Mutations in this gene cause familial juvenile nephronophthisis type 1, a kidney disorder involving both tubules and glomeruli. Defects in this gene are also associated with Senior-Loken syndrome type 1, also referred to as juvenile nephronophthisis with Leber amaurosis, which is characterized by kidney and eye disease, and with Joubert syndrome type 4, which is characterized by cerebellar ataxia, oculomotor apraxia, psychomotor delay and neonatal breathing abnormalities, sometimes including retinal dystrophy and renal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Category Type: Polyclonal Antibody
Research Areas: Cell Biology, Signal Transduction
Synonyms: JBTS4, Juvenile nephronophthisis 1 protein, Nephrocystin 1, nephronophthisis 1 (juvenile) , Nephronophthisis, NPH1, NPHP1, SLSN1
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: BC009789
Clonality: Polyclonal
Immunogen: Fusion protein of human NPHP1
Clone #:
Conjugation: Unconjugated
Swissprot: O15259
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1.32 mg/mL
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification method: Antigen affinity purification
Application: IHC, ELISA
Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000
Storage: Store at -20°C. Avoid freeze / thaw cycles.