NPM1 Polyclonal Antibody | G-AB-12695
- 3 to 5 Working Days
- Human, Mouse, Rat
NPM1 Polyclonal Antibody | G-AB-12695 | Gentaur Antibodies
Overview: Nucleophosmin (NPM1, B23) is a putative ribosome assembly factor with a high affinity for peptides containing nuclear localization signals (NLSs) . The transport of proteins across the nuclear envelope is a selective, multistep process involving several cytoplasmic factors. Proteins must be recognized as import substrates, dock at the nuclear pore complex and translocate across the nuclear envelope in an ATP-dependent fashion. Several cytosolic and nuclear proteins that are central to this process have been identified. The 38 kDa nuclear protein nucleophosmin is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Synonyms: B23, MGC104254, NO38, NPM, NPM, NPM1, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Nucleophosmin (nucleolar phosphoprotein B23 numatrin) , Nucleophosmin, nucleophosmin nucleoplasmin family member 1, Nucleophosmin/nucleoplasmin family member 1, Numatrin
Reactivity: Human, Mouse, Rat
Gene ID: 18148
Immunogen: Recombinant Mouse Nucleophosmin protein
Calculated MW: 32 kDa
Observed MW: 37 kDa
Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Purification method: Antigen Affinity Purification
Application: WB, IHC
Dilution: WB 1:10000-1:20000 IHC 1:200-1:500
Storage: Store at -20℃. Avoid freeze / thaw cycles.