NPM1 Polyclonal Antibody | G-AB-12695

NPM1 Polyclonal Antibody | G-AB-12695 | Gentaur Antibodies

Overview: Nucleophosmin (NPM1, B23) is a putative ribosome assembly factor with a high affinity for peptides containing nuclear localization signals (NLSs) . The transport of proteins across the nuclear envelope is a selective, multistep process involving several cytoplasmic factors. Proteins must be recognized as import substrates, dock at the nuclear pore complex and translocate across the nuclear envelope in an ATP-dependent fashion. Several cytosolic and nuclear proteins that are central to this process have been identified. The 38 kDa nuclear protein nucleophosmin is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: B23, MGC104254, NO38, NPM, NPM, NPM1, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Nucleophosmin (nucleolar phosphoprotein B23 numatrin) , Nucleophosmin, nucleophosmin nucleoplasmin family member 1, Nucleophosmin/nucleoplasmin family member 1, Numatrin

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 18148

Accession #:

Clonality: Polyclonal

Immunogen: Recombinant Mouse Nucleophosmin protein

Clone #:

Conjugation:

Swissprot: Q61937

Santa Cruz:

Calculated MW: 32 kDa

Observed MW: 37 kDa

Concentration: 1mg/mL

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.

Purification method: Antigen Affinity Purification

Application: WB, IHC

Dilution: WB 1:10000-1:20000 IHC 1:200-1:500

Storage: Store at -20℃. Avoid freeze / thaw cycles.

NPM1 Polyclonal Antibody DataSheet