PGC1 alpha Polyclonal Antibody | G-AB-07661

PGC1 alpha Polyclonal Antibody | G-AB-07661 | Gentaur Antibodies

Overview: The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs) . It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism

Synonyms: PPARGC1A, LEM6, PGC-1 (alpha) , PGC-1alpha, PGC-1v, PGC1, PGC1A, PPARGC1, PPARG coactivator 1 alpha, PGC1 alpha

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 10891

Accession #:

Clonality:

Immunogen: A synthetic peptide of human PGC1 alpha (NP_037393.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9UBK2

Santa Cruz:

Calculated MW: 14 kDa/30 kDa/31 kDa/33 kDa/77 kDa/89 kDa/91 kDa

Observed MW: 110 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PGC1 alpha Polyclonal Antibody DataSheet