Phospho-ACACA (S79) Polyclonal Antibody | G-AB-12545

Phospho-ACACA (S79) Polyclonal Antibody | G-AB-12545 | Gentaur Antibodies

Overview: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.

Category Type: Phosphorylated antibody

Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms: ACACA, ACAC, ACACAD, ACC, ACC1, ACCA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 31

Accession #:

Clonality:

Immunogen: A phospho specific peptide corresponding to residues surrounding S79 of human ACACA

Clone #:

Conjugation: Unconjugated

Swissprot: Q13085

Santa Cruz:

Calculated MW: 257 kDa/259 kDa/265 kDa/269 kDa

Observed MW: 266 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-ACACA (S79) Polyclonal Antibody DataSheet