Phospho-ATM (S1981) Polyclonal Antibody | G-AB-12472

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$281.00 - $569.00
SKU:
G-AB-12472
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human
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Phospho-ATM (S1981) Polyclonal Antibody | G-AB-12472 | Gentaur Antibodies

Overview: The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.

Category Type: Phosphorylated antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1, ATM

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 472

Accession #:

Clonality:

Immunogen: A synthetic phosphorylated peptide around S1981 of human ATM (NP_000042.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q13315

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-ATM (S1981) Polyclonal Antibody DataSheet

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