Phospho-Estrogen Receptor alpha（S118） Polyclonal Antibody | G-AB-12521

Phospho-Estrogen Receptor alpha（S118） Polyclonal Antibody | G-AB-12521 | Gentaur Antibodies

Overview: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.

Category Type: Phosphorylated antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Signal Transduction

Synonyms: ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1, ER alpha

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 2099

Accession #:

Clonality:

Immunogen: A phospho specific peptide corresponding to residues surrounding S118 of human Estrogen Receptor alpha

Clone #:

Conjugation: Unconjugated

Swissprot: P03372

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:100 IF 1:100-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-Estrogen Receptor alpha（S118） Polyclonal Antibody DataSheet