Phospho-γH2A.X (S139) Polyclonal Antibody | G-AB-12511
- 3 to 5 Working Days
- Human, Mouse, Rat
Phospho-γH2A.X (S139) Polyclonal Antibody | G-AB-12511 | Gentaur Antibodies
Overview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
Category Type: Phosphorylated antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Synonyms: H2A.X, H2A/X, H2AX, Histone H2AX, H2AFX, histone H2AX, gamma H2A.X, γH2AX
Reactivity: Human, Mouse, Rat
Gene ID: 3014
Immunogen: A synthetic phosphorylated peptide around S139 of human γH2A.X (NP_002096.1) .
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC, IF
Dilution: IHC 1:50-1:100 IF 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.